Antioxidant efficacy of Cynodon dactylon leaf protein against ELA implanted swiss albino mice

The levels of enzymic and non enzymic antioxidants were determined in Ehrlich’s Lymphoma Ascite (ELA) transplanted Swiss albino mice treated with the protein fraction of Cynodon dactylon (Cdpf). ELA induced mice showed significant decrease in the level of enzymic antioxidants like catalase (73.43 to 55.03), superoxide dismutase (4.49 to2.47) and glutathione peroxidase (48.48 to 36.98) in units/mg protein and non enzymic antioxidant like vitamin A (7.18 to 3.25), vitamin E (8.55 to 3.18) in μg/g protein and reduced glutathione (2.38 to 1.65) in nmoles/g protein which indicated the production of free radicals in the liver. Administration of protein fraction to the ELA induced mice showed enhanced level of enzymic antioxidants (69.18, 4.11 and 49.39 units/mg protein) and non enzymic antioxidants (5.63, 5.20 μg/g protein and 3.43 nmoles/g protein) respectively which proved their protective action against the free radical damage caused by ELA tumor cells and maintains the normal function of the organ and confirmed their antioxidant activity.